Tropical virus serology

Travel dates, locations and clinical presentation must be provided to enable appropriate testing. Both Leptospira and Zika testing will not be performed without relevant details. For further guidance please refer to Public Health England's Rare and Imported Pathogens Laboratory (RIPL) Specimen referral guidelines and service user manual.

Referred to Rare and Imported Pathogens Laboratory, Public Health England, Porton, Salisbury, Wiltshire SP4 0JG
 

Please discuss with the Consultant Virologist before requesting if further clinical guidance is required.

Pathogens

Pathogens relevant to the area of travel, travel dates and other clinical details will be tested. Please ensure that clinical details are provided to ensure appropriate testing.

Tests and samples

(Smaller tubes are available for paediatric samples)

Dengue, West Nile, Japanese encephalitis, TBE, Yellow fever.

Flavivirus, IgG/IgM ELISA and PCR

Clotted blood (gold cap, 5 mL tube)
 

Chikungunya

Alphavirus IgG/IgM ELISA and PCR

Clotted blood (gold cap, 5 mL tube)
EDTA blood (purple cap, 4 mL tube)
 

Rift Valley fever, Sandfly fever

Phlebovirus PCR

Clotted blood (gold cap, 5 mL tube), or
EDTA blood (purple cap, 4 mL tube), or
CSF
 

Lassa virus

Arenavirus PCR

Clotted blood (gold cap, 5 mL tube), or
EDTA blood (purple cap, 4 mL tube), or
Urine in white-topped Universal container.
 

Ebola, Marberg.

Filovirus PCR

Clotted blood (gold cap, 5 mL tube), or
EDTA blood (purple cap, 4 mL tube).
 

C.burnetii, O.tsutsugamushi, epidemic typhus, spotted fever.

Rickettsia IgG/IgM IF and PCR

Clotted blood (gold cap, 5 mL tube)
 

Leptospira

Leptospira IgM ELISA /PCR

Clotted blood (gold cap, 5 mL tube)
 

Zika virus.

Zika testing for asymptomatic pregnant women and travellers is not available.

Zika IgG / IgM ELISA and PCR.

Clotted blood (gold cap, 5 mL tube), or
Urine in white-topped Universal container.
 

Turnaround time

see virology and microbiological serology turnaround times.

Enquiries

Microbiology (Virology and Serology), ext. 64627