Virology and microbiological serology turnaround times

 

Quoted turnaround times are the times from receipt of specimen into the laboratory to 90% of reports leaving the laboratory. Stated times are based on normal working hours, Monday to Friday, excluding statutory bank and public holidays.

Serology

The following tests are done daily (Monday to Friday), with a turnaround time of 2-5 days*.

*Ranges are given where tests may be ordered individually or in combination (necessitating sequential testing on a single sample) - reports may not be issued until all tests are completed.

Hepatitis A IgG antibody (HAV IgG)
Hepatitis A IgM antibody (HAV IgM)
Hepatitis B surface antigen (HBsAg)
Hepatitis B surface antigen Neutralisation
Hepatitis B surface antibody (Anti-HBs)
Hepatitis B total core antibody (Anti-HBc)
Hepatits B core IgM antibody (Anti-HBc IgM)
Hepatitis B e antibody (Anti-HBe)
Hepatitis B e antigen (HBeAg)
Hepatitis C antibody (Anti-HCV)
HIV 1/2 antigen/antibody screen (Architect)
HIV 1/2 confirmation (Vidas/Immunocomb)
Treponema EIA (syphilis screen)
Treponema confirmation (TPHA/RPR)
HTLV I/I antibody (Anti-HTLV I/II)
Measles IgG antibody
Measles IgM antibody
Mumps IgG antibody
Mumps IgM Antibody
Varicella zoster IgG antibody (VZV IgG)
Varicella zoster IgM antibody (VZV IgM)
Herpes simplex 1 IgG antibody (HSV-1 IgG)
Herpes simplex 2 IgG antibody (HSV-2 IgG)
Cytomegalovirus IgG antibody (CMV IgG)
Cytomegalovirus IgG avidity (CMV IgG Avidity)
Cytomegalovirus IgM antibody (CMV IgM)
Epstein Barr EBNA IgG antibody (EBV EBNA IgG)
Epstein-Barr VCA IgG antibody (EBV VCA IgG)
Epstein-Barr VCA IgM antibody (EBV VCA IgM)
Rubella IgG antibody
Rubella IgM antibody
Toxoplasma IgG antibody
Toxoplasma IgM antibody
Parvovirus IgG antibody
Parvovirus IgM antibody
Borrelia burgdorferi antibody (Lyme)
Anti-streptolysin O titre (ASO)

The following tests are done as needed (Monday to Friday), with a turnaround time of 7 days.

Cryptococcal antigen (serum or CSF)
Helicobacter pylori IgG antibody (done weekly)
Leptospira antibody

Molecular

Test/marker Frequency of testing Turnaround time
Cytomegalovirus (CMV) DNA (quantitative) 1-2x a week 7 days
Epstein-Barr (EBV) DNA (quantitative) Weekly 7 days
Hepatitis B (HBV) DNA (quantitative) Bi-weekly 14 days
Hepatitis C (HCV) RNA (quantitative) Weekly 7 days
Human immunodeficiency virus 1 (HIV-1) RNA (quantitative) Daily 5 days
Herpes simplex (HSV) DNA (qualitative) Daily 5 days
Parvovirus B19 DNA (quantitative) As needed 7 days
Varicella zoster (VZV) DNA (qualitative) As needed 7 days
Mumps RNA (qualitative) As needed 7 days

Respiratory Multiplex [influenza (A/HINI(Swine)/B), RSV( A/B), adenovirus, para-influenza (1-4), bocavirus, rhinovirus, enterovirus, parechovirus, Mycoplasma pneumoniae], Human metapneumovirus (A/B)

Daily 5 days
Eye Multiplex (HSV 1/2, VZV, adenovirus, Chlamydia trachomatis) Daily 5 days
Brain Multiplex (HSV 1/2 , VZV, mumps, enterovirus) Daily 5 days
Vesicular Rash Multiplex (HSV 1/2, VZV) Daily 5 days
Fever & Rash Multiplex (measles, HHV 6/7, parvovirus B19, enterovirus) Daily 5 days
Chlamydia trachomatis DNA (genital) Daily 5 days
Neisseria gonorhhoea DNA (genital) Daily 5 days
Gastroenteritis Multiplex (norovirus, astrovirus, rotavirus, adenovirus, sapovirus) Discuss with consultant 5 days
ACE Triplex (adenovirus, CMV, EBV) Daily 5 days

Rapid Antigen Detection

Legionella Urine Antigen - run daily, 2 day turnaround.

Referrals

Primary referral tests (no work done locally) - 5-10 days

Confirmatory referral tests - 5 -10 days from date of referral.