Lymphocyte subsets (B, T, NK cell counts)

 

Alternative names, keywords

 

Samples required

EDTA blood (purple cap/ black cap ring, 4 mL tube). Smaller tubes are available for paediatric samples.

Must be tested within 48 hours – stored locally at room temperature. Not tested at weekends or Bank Holidays, however samples may be tested on Saturday mornings provided they arrive before 10am.

Test indications

For immune disorder investigations and some drug monitoring (e.g. Rituximab).

Reference range

T Cells (CD3+) see CD4/8 counts (T Lymphocyte subsets)

  B cells (CD19+) NK Cells (CD16+56+)
   %

Absolute count

(106/L, cells/µL)

%

Absolute count

(106/L, cells/µL)

Adult 6 - 19 100 - 500 7 - 31 90 - 600

Source: Comans-Bitter et al, Netherlands 1997, n=51

Note change to adult reference ranges from 5.11.18

  B cells (CD19+) NK Cells (CD16+56+)
Paediatric  %

Absolute count

(106/L, cells/µL)

 %

Absolute count

(106/L, cells/µL)

1 day to 1 week 5 - 22 40 - 1100 6 - 58 100 - 1900
1 week to 2 months 4 - 26 600 - 1900 3 - 23 200 - 1400
2 to 5 months 14 - 39 600 - 3000 2 - 14 100 - 1300
5 to 9 months 13 - 35 700 - 2500 2 - 13 100 - 1000
9 to 15 months 15- 39 600 - 2700 3 - 1 200 - 1200
15 to 24 months 17 - 41 600 - 3100 3 -16 100 - 1400
2 to 5 years 14 - 44 200 - 2100 4 - 23 100 - 1000
5 to 10 years 10 - 31 200 - 1600 4 - 26 90 - 900
10 to 16 years 8 - 24 200 - 600 6 - 27 70 - 1200

 

Turnaround time

Results within 2 working days.

Enquiries

Haematology (Immunohaematology)