Immunoglobulins

 

Alternative names, keywords

IgG, IgA, IgM

Samples required

Clotted blood (gold cap, 5 mL tube). Smaller tubes are available for paediatric samples.

Please also see myeloma screen.

Test indications

 

Factors affecting test performance/ results

As with other turbidimetric or nephelometric procedures, these tests may not provide accurate results in patients with monoclonal gammopathy, due to the unpredictable characteristics of paraproteins.

Results should always be assessed in conjunction with the patient’s medical history, clinical examination and other findings.

Reference range

Results are only valid if the Ig class is polyclonal (i.e. no paraproteins present).

Adults

 

 

IgG

7 - 16 g/L

IgA

0.7 - 4.0 g/L

IgM

0.4 - 2.3 g/L

 Paediatric ranges:

 

IgG (g/L)              

0 - 14 days 

3.20 - 12.1 g/L

15 days - <1 yr

1.48 - 6.31 g/L

1 - <4 years

3.17 - 9.94 g/L

4 - <10 years

5.01 - 11.7 g/L

10 - <19 years   

5.95 - 13.1 g/L
Note amended paediatric IgG reference ranges from January 2021 following amended information supplied by kit manufacturer.

 

 

IgA (g/L)

IgM (g/L)

0 - 1 years

0.0 - 0.83

0 - 1.45

1 - 3 years

0.20 - 1.00

0.19 - 1.46

4 - 6 years

0.27 - 1.95

0.24 - 2.10

7 - 9 years

0.34 - 3.05

0.31 - 2.08

10 - 11 years

0.53 - 2.04

0.31 - 1.79

12 - 13 years

0.58 - 3.58

0.35 - 2.39

14 - 15 years

0.47 - 2.49

0.15 - 1.88

16-19 years

0.61 - 3.48

0.23 - 2.59

Source: Roche Cobas® IgG kit insert 2020-07, 11.0
Roche Cobas® IgA kit insert 02-2015, V5.0.0
Roche Cobas® IgM kit insert 05-2015, V6.0

Turnaround time

Same day

Enquiries

Biochemistry (Automation)