Alkaline phosphatase isoenzymes

Referred to Berkshire & Surrey Pathology Services, Frimley Park Hospital NHS Foundation Trust, Portsmouth Road, Frimley, Surrey GU16 7UJ
 

Alternative names, keywords

API, alk phos isoenzymes

Samples required

Clotted blood (gold cap, 5 mL tube). Smaller tubes are available for paediatric samples.

Test indications

For investigation of raised total ALP, although not helpful unless total ALP is >1.5 xULN

Indicated only if LFTs (including GGT) are normal, or liver source with additional bone contribution suspected.

Reference range

Male:

Total ALP: 40 - 130 U/L
Bone ALP: <97 U/L
Liver 1 ALP: <92 U/L
Liver 2 ALP: <14 U/L

Female:

Total ALP: 35 - 105 U/L
Bone ALP: <77 U/L
Liver 1 ALP: <75 U/L
Liver 2 ALP: <15 U/L
 

Turnaround time

Referral lab quotes turnaround time of 7 days, however additional time must be allowed for packing, despatch and delivery of sample, and return and processing of results.

Enquiries

Biochemistry (Referrals)