Alternative names, keywords

Alpha fetoprotein

Samples required

Clotted blood (gold cap, 5 mL tube). Smaller tubes are available for paediatric samples.

Test indications


Factors affecting test performance/ results

Biotin may interfere - samples should not be taken from patients receiving therapy with high biotin doses (i.e. > 5 mg/day) until at least 8 hours following the last biotin administration.

In rare cases, interference due to extremely high titres of antibodies to analyte-specific antibodies, streptavidin or ruthenium can occur.

Results should always be assessed in conjunction with the patient’s medical history, clinical examination and other findings.

Reference range

0 - 5.8 KU/L
Source: Roche Cobas® AFP kit insert, 01-2015, V13.0

Turnaround time

One working day


Biochemistry (Automation)