Gut hormones

Referred to Berkshire & Surrey Pathology Services, Frimley Park Hospital NHS Foundation Trust, Portsmouth Road, Frimley, Surrey GU16 7UJ

Alternative names, keywords

Vasoactive intestinal polypeptide, VIP, pancreatic polypeptide, PP, gastrin, neurotensin, somatostatin, chromogranin A, chromogranin B, CART, cocaine- and amphetamine-related transcript.

Samples required

3x EDTA blood (purple cap/ yellow cap ring, 4 mL tube) for full profile.

Bring to lab immediately, on ice. Samples must be separated within 15 minutes of venepuncture. Do not send via pneumatic tube (pod) system.

Please indicate hormones required on request form. Patient must be fasting (without water for gastrin), unless for Chromogranin A and/or B only.

Test indications


Test information

For gastrin, patient must be fasting and off antisecretory medication:

Proton pump inhibitors e.g. omeprazole - stop for 2 weeks
H2 antagonists e.g. ranitidine - stop for 3 days
Alkalis - stop for 18h

Reference range

Vasoactive intestinal polypeptide (VIP)

< 30 pmol/L

Pancreatic polypeptide (PP)

< 300 pmol/L


< 40 pmol/L


< 50 pmol/L

Neurotensin (available on special request only)

< 100 pmol/L


< 150 pmol/L

Chromogranin A

< 60 pmol/L

Chromogranin B

< 150 pmol/L

CART (cocaine- and amphetamine-related transcript) (available on special request only)

< 130 pmol/L


Turnaround time

Referral lab quotes turnaround time of 15 days, however additional time must be allowed for packing, dispatch and delivery of sample, and return and processing of results.


Biochemistry (Referrals)